EMAL4 Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene result

Mutations in this gene result in Currarino syndrome

This innovative and easy-to-use kit allows for quick and reliable detection of IL-10 levels in mouse samples

Containing six NHR (neuralized homology repeat) domains

Related pseudogenes have been defined on chromosomes 8 and 20

subunit:Interacts with both NF-kappa-B inhibitor alpha (NFKBIA) and beta (NFKBIB) in vitro

EMAL4 Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene resultThis gene is a member of the echinoderm microtubule associated protein like family. The encoded WD repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene which generates EML4 ALK fusion transcripts is one of the primary mutations associated with non small cell lung cancer. Alternative splicing of this gene results in two transcript variants.