POGK Rabbit Polyclonal Antibody, 50ul Primary Antibodies Mutation analysis of this gene

Mutation analysis of this gene has not revealed any mutation which causes the CPX disorder

There are multiple pseudogenes of RPL10 dispersed throughout the genome

Thr-538 (activation loop of the kinase domain)| Ser-676 (turn motif) and Ser-695 (hydrophobic region)| need to be phosphorylated for its full activation

playing a role in T-cell and B-cell development and activation

The encoded protein binds RNA and interacts with two other EJC core components

POGK Rabbit Polyclonal Antibody, 50ul Primary Antibodies Mutation analysis of this geneThe exact function of the protein encoded by this gene is not known. However this gene product contains a KRAB domain (which is involved in protein protein interactions) at the N terminus and a transposase domain at the C terminus suggesting that it may belong to the family of DNA mediated transposons in human.