HP1 gamma(Phospho-Ser83) Rabbit Polyclonal Antibody, 20ul Custom Peptide Synthesis Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria

Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2)

It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas

|subunit:Heterotrimer of an alpha catalytic subunit| a beta and a gamma non-catalytic regulatory subunits

This complex catalyzes the formation of cyclin B-ubiquitin conjugate

HP1 gamma(Phospho-Ser83) Rabbit Polyclonal Antibody, 20ul Custom Peptide Synthesis Multiple alternatively spliced transcript variantsAt the nuclear envelope the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone