SAE1 Polyclonal Antibody, 100ul Metabolic enzymes cofactor:Binds 2 cobalt ions per

cofactor:Binds 2 cobalt ions per subunit

This gene is a putative tumor suppressor

and sequence variants of this gene are also associated with atrial fibrillation

Sumoylation inhibits the AP-1 transcriptional activity and is| itself| inhibited by Ras-activated phosphorylation on Thr-232

This protein resembles yeast Prp16 more closely than other DEAD/H family members

SAE1 Polyclonal Antibody, 100ul Metabolic enzymes cofactor:Binds 2 cobalt ions perPosttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO activating enzyme for the sumoylation of proteins.