Erbin Rabbit Polyclonal Antibody, 50ul[BT-AP09695] Deep Well Plates May be involved in actively

May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

reducing the research

and protein-protein interactions

Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy| an autosomal recessive disorder of unregulated and high insulin secretion

Expression of the human protein has been detected in uterus

Erbin Rabbit Polyclonal Antibody, 50ul[BT-AP09695] Deep Well Plates May be involved in activelyThis gene is a member of the leucine rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.