Rat Macrophage Migration Inhibitory Factor, MIF ELISA Kit, 96T Metabolic enzymes tool compounds PubMed: 27780864

PubMed: 27780864

subunit:Identified in the spliceosome C complex

The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline

It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity)

Mediates the release of cytokines/chemokines such as TNF

Rat Macrophage Migration Inhibitory Factor, MIF ELISA Kit, 96T Metabolic enzymes tool compounds PubMed: 27780864Pro inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase