MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes This gene is up-regulated by

This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation

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results in chronic myeloproliferative disorder with eosinophilia

is located on chromosome 6

This protein has been shown to be up-regulated in tumors| especially in breast tumors| and thus it is associated with tumor invasiveness

MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes This gene is up-regulated byThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript