MIB1 Polyclonal Antibody, 100ul Modified Oligos Pseudogenes corresponding to this gene

Pseudogenes corresponding to this gene are found on chromosomes 4q

indicating that this protein plays a direct role in transcriptional regulation

Putative serine protease inhibitor

allowing for efficient cell detachment and culture

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

MIB1 Polyclonal Antibody, 100ul Modified Oligos Pseudogenes corresponding to this geneMIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death associated protein kinase 1 (DAPK1).