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UBP6 Polyclonal Antibody, 50ul sgRNA Oligos an alternative non-homologous end-joining (NHEJ)

SKU: 48342016254

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UBP6 Polyclonal Antibody, 50ul sgRNA Oligos an alternative non-homologous end-joining (NHEJ)Catalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,disease: Involved in tumorigenesis.,Has an ATP independent isopeptidase activity, cleaving at the C terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous: The USP6 gene only exists in the primate lineage.,Belongs to the peptidase C19 family.,Contains 1 Rab GAP TBC domain.,tissue specificity: Testis

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Description

an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA (PubMed: 25642963

The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development

CEP41 (centrosomal protein 41) encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain

May fulfill a function related to the motile behaviors of developing neurons

is a nuclear receptor protein that in humans is encoded by the THRB gene

UBP6 Polyclonal Antibody, 50ul sgRNA Oligos an alternative non-homologous end-joining (NHEJ)Catalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,disease: Involved in tumorigenesis.,Has an ATP independent isopeptidase activity, cleaving at the C terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous: The USP6 gene only exists in the primate lineage.,Belongs to the peptidase C19 family.,Contains 1 Rab GAP TBC domain.,tissue specificity: Testis

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