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doi: 10.1677/joe.0.1600075 41 WeberPSToelboellTChangLCTirrellJDSaamaPMSmithGWet al

Glutathione is widely known as the master antioxidant because of its central role in protecting cells from oxidative stress

Additionally, pathological proteins of ALS can be secreted into the extracellular matrix, and these pathological proteins are sensed by microglia, causing microglial activation and pro-inflammatory effect that are harmful to co-cultured motor neurons