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IL-1F8 Polyclonal Antibody, 20ul Erlenmeyer Flasks The expression of this receptor

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IL-1F8 Polyclonal Antibody, 20ul Erlenmeyer Flasks The expression of this receptorInterleukin 36 beta encoded by IL36B is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12 stranded beta trefoil structure that is conserved between IL1A (IL A alpha) and IL1B (IL 1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Description

The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors

The basic leucine zipper ATF-like transcription factor encoded by BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors

A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis

The CD48 antigen is found on the surface of lymphocytes and other immune cells

Among its related pathways are Metabolism of proteins and O-linked glycosylation

IL-1F8 Polyclonal Antibody, 20ul Erlenmeyer Flasks The expression of this receptorInterleukin 36 beta encoded by IL36B is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12 stranded beta trefoil structure that is conserved between IL1A (IL A alpha) and IL1B (IL 1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

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