TRAP240 Polyclonal Antibody, 50ul[BT-AP09183] NGS Oligos Upon activation of the alternative

Upon activation of the alternative pathway

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells

Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy

Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3

The protein is implicated in adipogenesis and erythropoiesis

TRAP240 Polyclonal Antibody, 50ul[BT-AP09183] NGS Oligos Upon activation of the alternativeMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.