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[DOI] [PubMed] [Google Scholar] 16.Saida T., Koga H

Biochimica et Biophysica Acta (BBA)-Molecular Cell Res 1868(8): 119041 Ribeiro RA, Wanderley CW, Wong DV, Mota JMS, Leite CA, Souza MH, Lima-Junior RC (2016) Irinotecan-and 5-fluorouracil-induced intestinal mucositis: insights into pathogenesis and therapeutic perspectives

17 Zeze N, Kido-Nakahara M, Tsuji G, Maehara E, Sato Y, Sakai S, Fujishima K, Hashimoto-Hachiya A, Furue M, Nakahara T (2022) Role of ERK pathway in the pathogenesis of atopic dermatitis and its potential as a therapeutic target

They sit at the center of a $100 billion-plus market projected by the end of the decade

Tirzepatide-based evidence from the SURPASS (Researching Tirzepatide in Patients with Type 2 Diabetes for Glycemic Control and Weight Management) trials (SURPASS-1 NCT03954834 and SURPASS-5 NCT04039503) demonstrated dose-dependent, significant weight loss over 40 weeks compared with placebo, along with reductions in BMI and waist circumference [62, 63]