PDGF-B Polyclonal Antibody, 50ul Glassware this gene is down-regulated during

this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway

This gene encodes a nuclear-localized E3 ubiquitin ligase

Northern blotting studies have shown that TUBA1A expression is predominantly found in morphologically differentiated neurologic cells

including thyroid cancer

May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex

PDGF-B Polyclonal Antibody, 50ul Glassware this gene is down-regulated duringPDGFB (platelet derived growth factor subunit B) encodes a member of the protein family comprised of both platelet derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet derived growth factor subunit A. These proteins bind and activate PDGF