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AES Polyclonal Antibody, 50ul Buffer Solutions The chondroitin sulfate proteoglycan NG2

SKU: 40639133003

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AES Polyclonal Antibody, 50ul Buffer Solutions The chondroitin sulfate proteoglycan NG2The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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Description

The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells

Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity

This gene encodes a member of the CHIC family of proteins

Some haplotypes of this gene show a positive association with schizophrenia

a transmembrane region and a highly conserved cytoplasmic tail

AES Polyclonal Antibody, 50ul Buffer Solutions The chondroitin sulfate proteoglycan NG2The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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