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PPM1E Polyclonal Antibody, 50ul Plates & Dishes originally described in yeast as

SKU: 37209286554

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SEK162.00 SEK194.00

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PPM1E Polyclonal Antibody, 50ul Plates & Dishes originally described in yeast asThis gene encodes a member of the PPM family of serine threonine protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine threonine protein kinase PAK 1, 5' AMP activated protein kinase (AMPK) and the multifunctional calcium calmodulin dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.

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Description

originally described in yeast as cell division cycle regulatory proteins

and thereby enhances TGF-beta target-gene transcription

analgesic and aversive actions of synthetic opioids

A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome

suggesting that it is required for kinetochore formation

PPM1E Polyclonal Antibody, 50ul Plates & Dishes originally described in yeast asThis gene encodes a member of the PPM family of serine threonine protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine threonine protein kinase PAK 1, 5' AMP activated protein kinase (AMPK) and the multifunctional calcium calmodulin dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.

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