TAF II p140 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Mutations in CDKN1C are implicated

Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome

Receptor binding leads to an increase in the cytosolic calcium ion concentration

This FAD-binding protein forms homodimers and reduces quinones to hydroquinones

which could bind and inhibit the chaperone activity of Hsc70/Hsp70

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TAF II p140 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Mutations in CDKN1C are implicatedThe highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box binding protein (TBP; MIM 600075) and a set of TBP associated factors (TAFs), including TAF3 (TATA box binding protein associated factor 3). TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors.