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MLH1 Polyclonal Antibody, 20ul Rotator and a role for autophagy

SKU: 34587797231

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MLH1 Polyclonal Antibody, 20ul Rotator and a role for autophagyMLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full length natures have not

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and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed

DDX20 encodes a DEAD box protein

This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage

The protein encoded by CLEC6A (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold

MLH1 Polyclonal Antibody, 20ul Rotator and a role for autophagyMLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full length natures have not

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