c-Fos(Phospho Ser374) Polyclonal Antibody, 20ul Centrifugal Filter This protein has E3 ligase

This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus

The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells

Additional splice variation has been identified but the full-length nature of these transcripts has not been determined

SspDl belongs to the regular restriction enzyme series and recognizes the G^GCGCC sequence

This protein contains an actin filament-binding domain| which together with its Dbl homology domain and one of its pleckstrin homology domains| can form microspikes

c-Fos(Phospho Ser374) Polyclonal Antibody, 20ul Centrifugal Filter This protein has E3 ligaseThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.