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Pdcd4 was initially demonstrated to preferentially inhibit translation of the luciferase mRNA possessing an artificial stem-loop structure at 5UTR with the free energy of 44.8 kcal/mol

Epub 2017 Jan 23 (Spanish) 20

This is not a complete medical list

suggesting that, at high concentrations, IGF-1 has effects not simply mediated by suppressing the effect of GH on hepatic insulin sensitivity [129, 209]