NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation The protein encoded by this

The protein encoded by this gene interacts with several other proteins

Rac GTPase activating protein 1 plays a regulatory role in cytokinesis

It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process

is a E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage

although its function has not been well established

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation The protein encoded by thisProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.