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Atrophin-1 Polyclonal Antibody, 50ul Lentiviral Packaging It is predicted to be

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Atrophin-1 Polyclonal Antibody, 50ul Lentiviral Packaging It is predicted to beDentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7 35 copies to 49 93 copies of a trinucleotide repeat (CAG CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative

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Description

It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors

delta and rho

Cleavage abolishes NF-kappa-B activation and enhances pro-apototic signaling through the TRADD-FADD interaction

Required for TNFRSF1A mediated activation of NF-kappa-B

The functional enzyme is thought to be a homodimer which uses FAD as a cofactor

Atrophin-1 Polyclonal Antibody, 50ul Lentiviral Packaging It is predicted to beDentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7 35 copies to 49 93 copies of a trinucleotide repeat (CAG CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative

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