DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification which can cause excessive production

which can cause excessive production of reactive oxygen species and cell stress

|tissue specificity:Skeletal muscle| liver| heart and kidney

This gene has also been linked to diabetic nephropathy

protein sorting

This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis

DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification which can cause excessive productionThe protein encoded by this gene is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4