PIPK I Gamma Polyclonal Antibody, 50ul Drying & Desiccation The protein encoded by SPINK6

The protein encoded by SPINK6 is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin

subunit:Binds the second PAH repeat of SIN3A (By similarity)

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resulting in its translocation to the nucleus where it phosphorylates nuclear targets

The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells

PIPK I Gamma Polyclonal Antibody, 50ul Drying & Desiccation The protein encoded by SPINK6This locus encodes a type I phosphatidylinositol 4 phosphate 5 kinase. Phosphatidylinositol 4 phosphate 5 kinase type 1 gamma catalyzes phosphorylation of phosphatidylinositol 4 phosphate, producing phosphatidylinositol 4,5 bisphosphate. Phosphatidylinositol 4 phosphate 5 kinase type 1 gammais found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital