Stat4 Polyclonal Antibody, 20ul[BT-AP14543] NGS Oligos The encoded protein (A-kinase anchoring

The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion

the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients

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another family member

Alternatively spliced transcript variants encoding distinct proteins have been described

Stat4 Polyclonal Antibody, 20ul[BT-AP14543] NGS Oligos The encoded protein (A-kinase anchoringThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.