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p53AIP1 Polyclonal Antibody, 100ul PCR Series A mutation in the serine-rich

SKU: 15440643095

4.6
USD141.00 USD187.00

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p53AIP1 Polyclonal Antibody, 100ul PCR Series A mutation in the serine-richTP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1) is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of TP53AIP1 is inducible by p53, and it is thought to play an important role in mediating p53 dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for TP53AIP1.

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Description

A mutation in the serine-rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610)

It contains a PR-domain and multiple zinc finger motifs

This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity

as well as bradykinin and kallidin

also known as protein located at seventeen-p-thirteen point three 1

p53AIP1 Polyclonal Antibody, 100ul PCR Series A mutation in the serine-richTP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1) is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of TP53AIP1 is inducible by p53, and it is thought to play an important role in mediating p53 dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for TP53AIP1.

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