SNAI2 Rabbit Polyclonal Antibody, 20ul Immunoassays Most of the mass of

Most of the mass of the pol I complex derives from the 2 largest subunits

High levels of expression of SGK1 may contribute to conditions such as hypertension and diabetic nephropathy

This gene has been referred to as USP16 and USP23 but is now known as USP21

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

Mutations in this gene have been shown to be a cause of Kabuki syndrome

SNAI2 Rabbit Polyclonal Antibody, 20ul Immunoassays Most of the mass ofThis gene encodes a member of the Snail family of C2H2 type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E box motifs and is also likely to repress E cadherin transcription in breast carcinoma. This protein is involved in epithelial mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.