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SPTC2 Rabbit Polyclonal Antibody, 20ul Vacuum Filter It has been implicated in

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SPTC2 Rabbit Polyclonal Antibody, 20ul Vacuum Filter It has been implicated inThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.

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Description

It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates

also designated precerebellin 1 or Cbln1

spinocerebellar ataxia type 6

Binds to DNA sequences containing the consensus nucleotide core sequence GGAA

It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity

SPTC2 Rabbit Polyclonal Antibody, 20ul Vacuum Filter It has been implicated inThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.

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