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There are several theories of anti-inflammatory components in the NRF-2 pathway that, in a selective manner, intervene in the inflammatory process at pulmonary, renal, urinary, and hepatic levels [19]

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*Correspondence: Jesse Roth, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Testing may include SAM, SAH, the SAM-to-SAH ratio, methionine, homocysteine, copper, ceruloplasmin, zinc, CBC, comprehensive metabolic panel, kidney function, liver markers and exposure-specific testing when appropriate