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The weight loss often achieved with GLP-1 medications provides additional metabolic benefits

Furthermore, oral administration of curcumin at doses of 5001000 mg/day has been reported to reduce menstrual pain by inhibiting uterine COX activity and mitigating prostaglandin-mediated uterine contractions (140)

The aforementioned cell wall and membrane targeting technologies can be harnessed in this context to enhance specificity

Second, the chicory inulin prebiotic included in the formulation works best when consumed alongside other dietary fiber and nutrients that support fermentation

We used FineGray sub-distribution hazard model analyses adjusted for sex and age to assess the association of sociodemographic variables, comorbidities and co-medications (defined in ESM Table 2) with the risk of treatment discontinuation

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