p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification This gene may contribute to

This gene may contribute to the transcriptional control of cell growth and differentiation

It binds beta-catenin and negatively regulates Wnt signaling pathway

The gene is part of a cluster of MMP genes on chromosome 11

and likely other mammals as well

developmental stage:Expressed in fetal liver (at protein level)

p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification This gene may contribute toMay be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin dependent kinase activity preventing phosphorylation of critical cyclin dependent kinase substrates and blocking cell cycle progression. induction: By p53 mezerein (antileukemic compound) and interferon beta. PTM: Phosphorylation of Thr 145 by Akt or of Ser 146 by PKC impairs binding to