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Chung E, Gillman M, Rushton D, Love C, Katz D

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Estrogen plays a well-established role in maintaining synaptic structure and density, particularly in the hippocampus, where it supports the physical connections between neurons that encode and retrieve memories

They took that one, and it got FDA approval for premenopausal women with sexual desire disorder. In 2019, it received FDA approval for the treatment of hypoactive sexual desire disorder (HSDD), a condition in which a persistently low interest in sex becomes distressing to the individual and isnt simply the result of aging, relationship difficulties, or another health condition