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Langford AA, Gelderblom H, Kunze RO, Pohle HD, Reichart PA

D., Muppidi, J

The evidence for low choline was especially consistent in the prefrontal cortex, the part of the brain that helps control thinking, emotions and behavior

doi: 10.1017/S0007114521005031 66

While common side effects like gastrointestinal upset are prevalent early on, they often subside, and serious adverse reactions are rare but require vigilant awareness

In our opinion, the measurement of serum selenium before supplementation might be useful in individual living in countries with high selenium intake, like the USA, to avoid the risk of potential disadvantages, but not individuals living in countries, like most European countries, where dietary selenium intake is low and high concentrations of serum selenium are very unlikely to be achieved with supplementation