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Up-regulated HMGB 1 in EAM directly led to collagen deposition by a PKC /Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB 1

Use of pantethine in combination with cholesterol-lowering drugs called statins (HMG-CoA reductase inhibitors) or with nicotinic acid (see the article on Niacin) may produce additive effects on blood lipids (42)

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Microsomal glutathione S-transferase (MGST3) is primarily localized to the endoplasmic reticulum and mitochondria-associated membranes