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Now, here's the clinically important implication, right

Immune cell infiltration into the brain after ischemic stroke in humans compared to mice and rats: a systematic review and meta-analysis

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Furthermore, our study reveals that metformin can alleviate ECM degradation and inflammation in chondrocytes exposed to H 2 O 2 by reducing oxidative stress-induced damages Additionally, our results establish that metformin exerts its antioxidant effects mainly through the Nrf2 signaling pathway, ultimately slowing OA progression (Fig

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