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Shedding may be temporary and linked to rapid weight loss-induced telogen effluvium

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Coverage suggests generics may come at ~50% lower monthly cost than innovator products (with some analyst commentary indicating sharp accessibility gains)

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Serotonin is synthesized from the amino acid tryptophan in a series of chemical reactions, of which the rate-limiting step is catalyzed by the enzyme tryptophan hydroxylase [178, 179], wherein SAMe functions as a methyl-donating cofactor in the rate-limiting step in these synthetic reactions to increase the levels of this neurotransmitter

Prescribers and patients should understand this residual exposure window when managing side effects or planning transitions to other therapies