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9 In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [ 3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days

These findings underscore NF-B as a central driver of immune aging, linking oxidative stress, inflammaging, autophagy suppression, and immune cell survival dysregulation