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Pleiotropy, MR-Egger and MR-PRESSO were used to evaluate pleiotropy of selected SNPs

doi: 10.1016/0003-9861(57)90241-2 65 SadeghipourO

[PubMed: 3000734] 67

et al., 2023) , Oscillibacter and Ruminococcus (Jiang et al., 2023), and Lachno Clostridium (Chen et al., 2023)

Estimates suggest oral bioavailability for peptides like BPC-157 may be only 1-2%, meaning massive doses would be required to achieve systemic effects