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Description

In brain, KYN is metabolized by microglia to the neurotoxic metabolite QUIN and by astrocytes to the beneficial metabolite kynurenic acid (KynA), thus, QUIN is increased and KynA is decreased in MDD patients brain

It is also used as an immunosuppressive in organ transplantation and autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, and multiple sclerosis (Kachur et al., 2023)

Distribution Channel Segment Analysis The hospital pharmacies segment, which is part of the distribution channel, is expected to garner the third-largest share in the semaglutide market by the end of the stipulated period