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some patients report that evening administration may help (though these medications can be administered at any time of day) For constipation: Ensure adequate hydration as tolerated, soluble fiber supplementation (psyllium), osmotic laxatives if needed (polyethylene glycol) For diarrhea: Adequate hydration with electrolyte replacement, continuation of antidiarrheal medications if previously prescribed For bloating: Avoiding carbonated beverages, limiting gas-producing foods, continuing probiotics if previously beneficial Continuation of established IBS therapies is generally appropriate

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We addressed this by incorporating a range of algorithms based on diagnosis, procedure and prescription claims, as well as frailty indicators and health service utilization

it was positioned for long-term scale