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SHMT and neurological disorders Impairments in 1C metabolism are linked to neurodevelopmental disorders and neurological diseases, manifesting as neuronal apoptosis, DNA damage, mitochondrial dysfunction, and oxidative stress [129]

While they did respond within 48 hours, the answer was quite brief and didnt provide as much detail as I had hoped

30347-9) in F344/N Rats (Gavage Studies)

Robinson K, Mayer EL, Miller DP, Green R, van Lente F, Gupta A, Kottke-Marchant K, Savon SR, Selhub J, Nissen SE, Kutner M, Topol EJ, and Jacobsen DW (1995)