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Seiwerth S, Sikiric P, et al

Overall, clearance of MHD is split ~50/50 between hepatic and renal clearance

Your doctor might also check your B12 levels with blood tests

It also has a role in producing red blood cells, as well as sex- and stress-related hormones

The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies