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Currently, concerning AD and other similar neurodegenerative disorders, the main treatment strategies are based on adjusting neurotransmission activity, including acetylcholinesterase inhibition as an attempt to increase cholinergic efficacy ( FIGURE 5 In another study, hematopoietic stem and progenitor cells were transplanted from mice with normal TREM2 function into mice with a defective TREM2 gene

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