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uPA Polyclonal Antibody, 50ul Electronic Pipette The different subunits arise from

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uPA Polyclonal Antibody, 50ul Electronic Pipette The different subunits arise fromPLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase type plasminogen activator (HMW uPA). HMW uPA can be further processed into the catalytically active low molecular weight

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Description

The different subunits arise from alternative splicing in the 3' coding region

the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH

The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene

The protein plays an important role in the regulation of electrolyte homeostasis

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uPA Polyclonal Antibody, 50ul Electronic Pipette The different subunits arise fromPLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase type plasminogen activator (HMW uPA). HMW uPA can be further processed into the catalytically active low molecular weight

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