Rock-1 Polyclonal Antibody, 100ul Inoculating Loops/Needles Take the risk and measure

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These transcription factors share a DNA-binding domain called the T-box

Studies in mouse suggest that this protein may function as a transcriptional repressor

Several transcript variants encoding two different isoforms have been found for this gene

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Rock-1 Polyclonal Antibody, 100ul Inoculating Loops/Needles Take the risk and measureROCK1 encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor.