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It gets easier with each injection

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Melanin granules accumulate above the nucleus of keratinocytes and are subsequently expelled with the exfoliation of epidermal cells

Given the availability of biomarkers for AD that can be used to measure brain pathology in vivo (including neuroimaging with positron emission tomography, CSF, and plasma biomarker analysis), studies are needed in older adults which measure AD biomarkers in the context of melatonin use