Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ 15-kD protein

15-kD protein

but also serve as scaffolding platforms for the assembly

This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium

Expression level and methylation status of this gene may be correlated with bone mineral density

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors

Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ 15-kD proteinAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.