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Seasonal effect on germinal vesicle-stage bovine oocytes is further expressed by alterations in transcript levels in the developing embryos associated with reduced developmental competence

Mechanism of mitophagy BNIP3 and NIX BNIP3 and BNIP3-like protein (BNIP3L)/Nip3-like protein X (NIX), members of the BCL2 family of BH3-only domain proteins, are localized to the OMM and function as pro-apoptotic proteins

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Patent EP0531708B1

Another limitation of this study is the lack of experiments exploring the molecular dynamics of NTZ in the improvement of MTX-mediated liver toxicity in more details in a cell culture model