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Tirzepatide produced 20.2% weight loss versus 13.7% for semaglutide at 72 weeks and has stronger body-composition results. Semaglutide has the longer safety history, cardiovascular outcomes data, kidney outcomes data, and an oral formulation. Oral semaglutide What about oral semaglutide (Rybelsus)

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Good Candidates for Oral Semaglutide: People with Severe Needle Phobia If you have genuine needle phobia (not just hesitation) that hasnt improved with: Cognitive behavioral therapy Exposure therapy Counseling or support Using the smallest gauge needles Then oral medication may be your only option to access GLP-1 therapy