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Troeman DP, Postma DF, van Werkhoven CH, Oosterheert JJ

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Therefore, besides its potent anti-oxidative stress effects, bilirubin may also attenuate inflammation in osteoarthritis (OA) by inhibiting the NF-B pathway (99), and some studies have suggested that osteoarthritis may promote the development of cancer, so bilirubin may serve to decrease the cancer development risk in this way (100)

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Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury